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Understanding acid reflux, non-acid reflux and hypersensitivity: a clear, practical guide
Most people use the word reflux to describe any burning or throat irritation after eating. In reality, there are several distinct mechanisms that behave differently and respond differently to treatment. If you’ve been told you have GORD, or if you have throat-heavy symptoms without heartburn, understanding these differences is the first step toward recovery.
Acid reflux
This is the classic form: stomach acid escapes upward when the lower oesophageal sphincter relaxes at the wrong time or pressure builds within the stomach. Acidic content meets a vulnerable lining and causes inflammation. PPIs such as omeprazole reduce acidity, allowing tissue to heal.Non-acid reflux
Here the material coming up is not acidic because it has been neutralised by food or medication. The problem is not the pH but the movement itself. Non-acid reflux can still trigger symptoms through distension, chemical components of food, or direct contact with the throat. This is why someone can feel burning or tightness even on high-dose PPIs.Hypersensitive oesophagus
Once inflamed, the oesophagus becomes more reactive. The lining and the nerves beneath it start to fire symptoms from minor stimuli: warm liquids, modest volumes of food, even air movement. In hypersensitivity, the amount of reflux may be small but the perception strong.Hypertensive upper oesophageal sphincter (UOS)
Some patients develop a tight, overactive upper sphincter. It can be a protective response to previous irritation. It generates throat pressure, difficulty swallowing certain textures and the sense of a lump. This is reversible as inflammation and nerve sensitivity calm.Strictures
Chronic inflammation can lead to narrowing. Dilation is effective, though it can trigger a temporary flare because the lining is briefly irritated. This does not mean you are back to square one. It is part of the repair cycle.The encouraging part is that all of this is reversible. With low-irritation habits, measured eating strategies and careful food selection, the oesophagus gradually desensitises and the sphincters return to more normal function. Most people eating a cautious diet can move toward normal eating within several months.
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